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publications

Au nano dumbbells catalyzed the cutting of graphene oxide sheets upon plasmon-enhanced reduction

Published in RSC advances, 2016

Wang, X., Zhu, M., Fu, W., Huang, C., Gu, Q., Zeng, T. H., … & Sun, Y. (2016). Au nano dumbbells catalyzed the cutting of graphene oxide sheets upon plasmon-enhanced reduction. RSC advances, 6(52), 46218-46225.

Graphene sheets manipulated the thermal-stability of ultrasmall Pt nanoparticles supported on porous Fe2O3 nanocrystals against sintering

Published in RSC advances, 2017

Dai, Y., Qi, X., Fu, W., Huang, C., Wang, S., Zhou, J., … & Sun, Y. (2017). Graphene sheets manipulated the thermal-stability of ultrasmall Pt nanoparticles supported on porous Fe 2 O 3 nanocrystals against sintering. RSC advances, 7(27), 16379-16386.

Self-assembly of defect-rich graphene oxide nanosheets with Na2Ti3O7 nanowires and their superior absorptive capacity to toxic dyes

Published in Nanotechnology, 2017

Sun, Y., Fu, W., Dai, Y., Huang, Y., Zhou, J., Huang, C., … & Lin, B. (2017). Self-assembly of defect-rich graphene oxide nanosheets with Na2Ti3O7 nanowires and their superior absorptive capacity to toxic dyes. Nanotechnology, 28(24), 245601.

Selective Etching of N-Doped Graphene Meshes as Metal-Free Catalyst with Tunable Kinetics, High Activity and the Origin of New Catalytic Behaviors

Published in Particle & Particle Systems Characterization, 2018

Dai, Y., Zhou, J., Huang, C., Gu, Q., Zeng, Y., Xu, W., … & Sun, Y. (2018). Selective Etching of N‐Doped Graphene Meshes as Metal‐Free Catalyst with Tunable Kinetics, High Activity and the Origin of New Catalytic Behaviors. Particle & Particle Systems Characterization, 35(4), 1700395.

Visible-light promoted catalytic activity of dumbbell-like Au nanorods supported on graphene/TiO2 sheets towards hydrogenation reaction

Published in Nanotechnology, 2018

Dai, Y., Zhu, M., Wang, X., Wu, Y., Huang, C., Fu, W., … & Sun, Y. (2018). Visible-light promoted catalytic activity of dumbbell-like Au nanorods supported on graphene/TiO2 sheets towards hydrogenation reaction. Nanotechnology, 29(24), 245703.

ZnO microfiltration membranes for desalination by a vacuum flow-through evaporation method

Published in Membranes, 2019

Dangwal, S., Liu, R., Bastatas, L. D., Echeverria, E., Huang, C., Mao, Y., … & Kim, S. J. (2019). ZnO microfiltration membranes for desalination by a vacuum flow-through evaporation method. Membranes, 9(12), 156.

Solventless Polymer-Grafted Mesh for Rapid and Efficient Oil–Water Separation

Published in ACS Appl. Polym. Mater., 2023

Huang, C., Zhu, M., & Mao, Y. (2023). Solventless Polymer-Grafted Mesh for Rapid and Efficient Oil–Water Separation. ACS Applied Polymer Materials.

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Solvent-free Drug Encapsulation for Zero-order Immunosuppressive Delivery from Three-Dimensional Devices

Published: November 11, 2020

Mitigation of immune responses is one of the major challenges in implanting medical devices. There is an unmet need to incorporate immunosuppressive drugs onto three-dimensional devices for effective delivery at the periphery of the devices. We encapsulated dexamethasone using a one-step, solvent-free method that formed coatings directly from the vapor phase onto device surfaces. Systematic studies demonstrated that by eliminating solvent use in the encapsulation process, the release profile of dexamethasone changed from two-day burst release to 60-day linear release at the same coating composition and parameters. The significant change in drug release kinetics was attributed to the efficient construction of mass transfer barrier around the drug using the vapor-based encapsulation, while the solution-based processing re-distributed and mixed the drug into the barrier coating, leading to burst release. We further regulated the drug release kinetics by crosslinking the encapsulation coating in situ, which not only provided dexamethasone release towards therapeutic dose below 2.0 µg/day but also enabled more than 90% reduction in daily release variation. In addition, we studied the dexamethasone release kinetics using the Korsmeyer-Peppas model. The drug release rate was linearly correlated with the drug load and the thickness of the encapsulation coating. We assessed the immunosuppressive effect of the released dexamethasone using microglia cell studies. On day one, the microglia activation expression was suppressed by 86% and 96% on encapsulated dexamethasone at 50 and 100 µg/cm^2, respectively. On day three, there was no significant difference between non-stimulated microglia and stimulated microglia on encapsulated dexamethasone at 50 and 100 µg/cm^2. We demonstrated that this novel solvent-free method can be extended to the encapsulation of other immunosuppressive drugs, providing a new platform to achieve sustained, zero-order drug delivery from three-dimensional medical devices.